What causes Kaposi's sarcoma?

Kaposi's sarcoma is caused by a virus called the human herpesvirus 8 (HHV-8), also known as the Kaposi's sarcoma-associated herpesvirus (KSHV). This virus is thought to bespread during sex, through saliva, or from a mother to her baby during birth. HHV-8 is a relatively common virus and the vast majority of people who have it will not develop Kaposi's sarcoma.It only seems to cause cancer in some people with a weakened immune system and in some people who havea genetic vulnerability to the virus. A weakened immune system allows the HHV-8 virus to multiply to high levels in the blood, which increases the chance it will cause Kaposi's sarcoma. Thevirusappears to alter the genetic instructions that control cell growth. This means some cells reproduce uncontrollably and form lumps of tissue known as tumours.
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