What causes pompholyx?

It's not clear exactly what causes pompholyx, but it may be triggered or made worse by: afungal skin infection this may be on the hands or at a distant site from the blisters (such as in between the toes) and will need treating a reaction to something that has touched your skin such as certain metals (particularly nickel) , detergents, household chemicals, soap, shampoo, cosmetic products or perfume stress sweating pompholyx is more common in spring and summer, in warmer climates, and inpeople with hyperhidrosis (excessive sweating)
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